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Kazuhiko Ino Selected Research

leucyl-cystinyl aminopeptidase

3/2006A novel role for placental leucine aminopeptidase (P-LAP) as a determinant of chemoresistance in endometrial carcinoma cells.
11/2004Placental leucine aminopeptidase (P-LAP) expression is associated with chemosensitivity in human endometrial carcinoma.
8/2004Regulatory role of membrane-bound peptidases in the progression of gynecologic malignancies.
1/2004Expression of placental leucine aminopeptidase is associated with a poor outcome in endometrial endometrioid adenocarcinoma.
4/2003Possible role of placental leucine aminopeptidase in the antiproliferative effect of oxytocin in human endometrial adenocarcinoma.

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Kazuhiko Ino Research Topics

Disease

51Neoplasms (Cancer)
11/2021 - 01/2003
28Carcinoma (Carcinomatosis)
10/2021 - 01/2002
21Ovarian Neoplasms (Ovarian Cancer)
12/2020 - 04/2005
13Endometrial Neoplasms (Endometrial Cancer)
01/2017 - 08/2003
12Neoplasm Metastasis (Metastasis)
08/2017 - 07/2004
9Adenocarcinoma
11/2015 - 01/2003
8Endometrioid Carcinoma
06/2016 - 03/2003
7Uterine Cervical Neoplasms (Cancer of the Cervix)
12/2021 - 06/2008
7Ovarian Epithelial Carcinoma
11/2010 - 04/2003
6Choriocarcinoma
01/2020 - 08/2003
4Hydatidiform Mole (Molar Pregnancy)
06/2020 - 01/2007
4Gestational Trophoblastic Disease (Trophoblastic Neoplasms, Gestational)
06/2020 - 08/2016
4Mucinous Adenocarcinoma (Mucinous Carcinoma)
07/2013 - 10/2006
3Melanoma (Melanoma, Malignant)
11/2021 - 02/2010
3Squamous Cell Carcinoma (Epidermoid Carcinoma)
11/2015 - 05/2004
2Ascites
08/2014 - 11/2007
2Leiomyoma (Uterine Fibroids)
12/2012 - 03/2011
2Disease Progression
05/2012 - 04/2008
1Spontaneous Abortion (Miscarriage)
04/2022
1Type 2 Diabetes Mellitus (MODY)
01/2021
1Amyloidosis
12/2020
1Stomatitis
01/2020
1Leukopenia
01/2020

Drug/Important Bio-Agent (IBA)

14EnzymesIBA
01/2017 - 04/2003
11Complementary DNA (cDNA)IBA
08/2014 - 04/2003
11Paclitaxel (Taxol)FDA LinkGeneric
01/2011 - 11/2004
11Dipeptidyl Peptidase 4 (Dipeptidyl Peptidase IV)IBA
02/2010 - 05/2002
8Proteins (Proteins, Gene)FDA Link
12/2020 - 04/2003
8Angiotensin IIIBA
05/2011 - 08/2003
7Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA
11/2015 - 04/2008
7Peptides (Polypeptides)IBA
01/2005 - 03/2003
6Indicators and Reagents (Reagents)IBA
10/2021 - 04/2008
6Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
04/2005 - 12/2003
5Small Interfering RNA (siRNA)IBA
01/2012 - 01/2007
5Carboplatin (JM8)FDA LinkGeneric
01/2012 - 11/2004
5leucyl-cystinyl aminopeptidaseIBA
03/2006 - 04/2003
4Biomarkers (Surrogate Marker)IBA
01/2021 - 10/2016
4Circulating Tumor DNAIBA
11/2020 - 11/2018
4Formaldehyde (Formol)FDA Link
11/2018 - 01/2004
4ParaffinIBA
11/2018 - 01/2004
4PlatinumIBA
01/2012 - 11/2004
4Cisplatin (Platino)FDA LinkGeneric
01/2011 - 03/2006
4Cadherins (E-Cadherin)IBA
01/2007 - 05/2003
4Neprilysin (Neutral Endopeptidase)IBA
03/2005 - 04/2003
4Oxytocin (Pitocin)FDA LinkGeneric
08/2004 - 04/2003
3Tryptophan (L-Tryptophan)FDA Link
01/2021 - 01/2017
3CytokinesIBA
04/2019 - 08/2014
3Pharmaceutical PreparationsIBA
01/2012 - 02/2010
3Endothelin-1 (Endothelin 1)IBA
03/2005 - 08/2004
3Leucyl Aminopeptidase (Peptidase S)IBA
01/2005 - 08/2003
3Glutamyl Aminopeptidase (Aspartyl Aminopeptidase)IBA
08/2004 - 08/2003
3Peptide Hydrolases (Proteases)FDA Link
08/2004 - 05/2004
2Phosphotransferases (Kinase)IBA
10/2021 - 11/2015
2Glucose (Dextrose)FDA LinkGeneric
10/2021 - 01/2007
2Chromogranin AIBA
07/2013 - 09/2003
2CollagenIBA
12/2012 - 03/2011
2Type 1 Angiotensin ReceptorIBA
05/2011 - 04/2005
2Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
05/2011 - 03/2006
2Collagen Type I (Type I Collagen)IBA
03/2011 - 02/2009
2GlypicansIBA
11/2010 - 01/2010
2paclitaxel 2'-ethylcarbonateIBA
02/2010 - 02/2008
2ProdrugsIBA
02/2010 - 02/2008
2Matrix Metalloproteinases (MMPs)IBA
01/2009 - 05/2003
2Matrix Metalloproteinase 2 (Gelatinase A)IBA
01/2009 - 03/2005
2Chemokine CXCL12IBA
01/2008 - 07/2004
2ubenimexIBA
07/2007 - 05/2007
2AminopeptidasesIBA
11/2006 - 12/2003
2AngiotensinsIBA
03/2006 - 01/2005
2Conditioned Culture MediaIBA
03/2005 - 01/2005
1gemeprostIBA
04/2022
1Immune Checkpoint InhibitorsIBA
11/2021
1pembrolizumabIBA
11/2021
1Dihydrotachysterol (AT 10)IBA
11/2021
1Sterol O-AcyltransferaseIBA
10/2021
1pitavastatin (itavastatin)FDA Link
10/2021
1Perilipin-2IBA
10/2021
1Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
10/2021
1PrionsIBA
12/2020
1SulfatasesIBA
12/2020
1Heparitin Sulfate (Heparan Sulfate)IBA
12/2020
1GlycosaminoglycansIBA
12/2020
1Amyloid (Amyloid Fibrils)IBA
12/2020
1CA-125 Antigen (CA 125 Antigen)IBA
01/2020
1Etoposide (VP 16)FDA LinkGeneric
01/2020
1Dactinomycin (Actinomycin)FDA LinkGeneric
01/2020
1Methotrexate (Mexate)FDA LinkGeneric
01/2020

Therapy/Procedure

13Drug Therapy (Chemotherapy)
01/2020 - 05/2004
10Hysterectomy
12/2021 - 05/2004
8Therapeutics
04/2019 - 04/2005
5Neoadjuvant Therapy
04/2020 - 01/2004
5Lymph Node Excision (Lymph Node Dissection)
09/2016 - 06/2008
2Curettage
06/2020 - 08/2016
2Adjuvant Chemotherapy
05/2017 - 01/2017
2Immunotherapy
11/2015 - 02/2011
2Radiotherapy
06/2015 - 06/2010
2Brachytherapy
09/2012 - 07/2012
2Aftercare (After-Treatment)
09/2012 - 01/2012
2Cytoreduction Surgical Procedures
02/2011 - 01/2006
1Surgical Instruments (Clip)
04/2022
1Minimally Invasive Surgical Procedures
12/2021